Park7 (DJ1) is linked to the preservation of mitochondrial function in PD, and the unique activation of DJ-1, Atg and interferon regulatory protein in the dual treatment group likely represents the activation of the antioxidant activation and autophagy stress response pathways [55], possibly in reponse to underrepresented transcripts involved in antioxidant activity, such as glutathione peroxidase (Fig 4A). This evidence concerns the gene PARK7 and Parkinson disease.