Cardiovascular SAEs were reported in only five patients: supraventricular tachycardia (n = 2, R‐CHOP group), atrial fibrillation (n = 1, R‐COMP group), myocardial infarction (n = 1, R‐CHOP group), and heart failure (n = 1, R‐CHOP group). This evidence concerns the gene DDIT3 and heart failure.