Immunodeficient NOD/scid-IL-2Rγcnull (NSG) mice were subcutaneously implanted with human HCT116 CRC cells and intravenously (i.v.)treated every other day with 1 mg/kg of PS-acet.-STAT3 peptide after tumors were established. The gene discussed is STAT3; the disease is colorectal carcinoma.