To further confirm our in vitro data shown in Figure 1 that PS-acet.-STAT3 peptide could bind to exportin 7 to inhibit STAT3-exportin 7 interaction and further downregulate STAT3 activity, we performed immunoprecipitation of the FAM-labeled PS-acet.-STAT3 peptide or endogenous STAT3, followed by Western blotting with homogenates prepared from HCT116 colon tumors from mice treated with PO- and PS-acet.-STAT3 peptides. Here, STAT3 is linked to colonic neoplasm.