Citrate treatment increased global catecholamine biosynthesis in the adrenal pheochromocytoma cell line MPC, an effect that was partially blunted by inhibition of mINDY with a small molecule inhibitor, previously shown to reduce citrate uptake and to improve metabolic control in obese mice in vivo (21). The gene discussed is SLC13A5; the disease is adrenal gland pheochromocytoma.