GRN and cancer: Further, these results suggest that progranulin plays a role in the proliferation of malignant hematopoietic cell lines similarly to other types of cancer cell lines, such as MCF-7, SKBR-3, RPMI8226, HeLa, H8, KKU-100, and HepG2 [2, 27, 32, 33, 34, 35].