To confirm the role of GPR56 in the proliferation of PD-1+ lymphocytes in chronic tonsillitis, palate tonsils of further the elder 39 patients with chronic tonsillitis were collected and analyzed PD-1 and Gpr56 transcripts by the same semi-quantitate RT-PCR method without separation of sex. Here, ADGRG1 is linked to Recurrent tonsillitis.