PRKAA1 and Hypoglycemia: The ventromedial hypothalamic nucleus (VMN), a prominent neuroanatomical component of the MBH, is a likely source of AMPK gluco-regulatory signaling as hypoglycemia increases AMPK phosphorylation in VMN neurons that express characterized gluco-inhibitory (γ-aminobutyric acid; GABA) or stimulatory (nitric oxide; NO) neurotransmitters [8],[9].