CD4+ T cells and CD4+/CD8+ ratio percentages, as well as IL-6 and IL-10, showed higher levels in the DM group than those in the NDM group; meanwhile, the CD4+ T cell percentage and IL-10 were higher in the DM group than those in the IFG group, which suggested the increased inflammatory response presented in COVID-19 patients with hyperglycemia. This evidence concerns the gene CD8A and diabetes mellitus.