As shown in Figure 1, the serum levels of IL-6, IL-2, IL-10, and INF-γ in the DM group were upregulated when compared with those in the NDM group (P < 0.05); the serum levels of TNF-α, IL-4, IL-2, IL-10, and INF-γ were significantly lower in the IFG group than those in the DM groups (P < 0.05); TNF-α level was lower in the NDM group than that in the IFG group (P < 0.05). The gene discussed is TNF; the disease is diabetes mellitus.