As shown in Figure 6, the expression profiles of 11 biomarker genes, including IL10RA, AOAH, CD48, IL32, CORO1A, GPR132, ITGAL, LCK, LCP1, RCSD1, and TBC1D10C, are significantly associated with overall survival of patients with metastatic melanoma on GEO GSE22154 dataset. The gene discussed is AOAH; the disease is metastatic melanoma.