CircMCTP1(9–12) was found to be highly up-regulated in JMML compared with HD (Figure 4 and Supplementary Figure 2) and with higher levels observed in NRAS patients, consistently according to RNA-seq (Figure 2C) and qRT-PCR data in the extended cohort (Figure 5A). This evidence concerns the gene NRAS and juvenile myelomonocytic leukemia.