We further constructed MAPK8IP1P2-stably overexpressing B-CPAP and K1 cells and endogenously knocked down MAPK8IP1P2 expression in B-CPAP and K1 cells, both of which expressed moderate levels of MAPK8IP1P2 compared with that in other thyroid cancer cell lines (Figure 2B). The gene discussed is MAPK8IP1P2; the disease is thyroid gland carcinoma.