Interestingly, we found that downexpression of MAPK8IP1P2 occurred in 4/9 (44.4%) thyroid cancer tissues without lymph node metastasis, and was 10/15 (66.7%) in thyroid cancer tissues with lymph node metastasis (Figure 1B). The gene discussed is MAPK8IP1P2; the disease is metastatic malignant neoplasm in the lymph nodes.