A gene-based prognostic model was established to evaluate the survival risk for each patient as follows: Risk score = 0.00710 × expression of PGK1 + 0.00187 × expression of SDC1 + 0.05107 × expression of NUP43 + 0.05599 × expression of NT5E + 0.00587 × expression of IL13RA1 + 0.05692 × expression of GCLC + 0.01385 × expression of CACNA1H + (-0.00535) × expression of P4HA1 + 0.011698 × expression of TSTA3 + 0.026129 × expression of MXI1 + 0.00305 × expression of STC1. We then analyzed the mutational status of these 11 selected genes in TCGA BC samples in the cBioPortal database. The gene discussed is STC1; the disease is breast cancer.