In the Cromer Head-Neck dataset, CXCL1, CXCL3, CXCL8, and CXCL13 were overexpressed in HNSCC samples in contrast with normal tissues, and the fold changes were 10.047, 2.522, 23.677, and 6.901, respectively (20). The gene discussed is CXCL1; the disease is head and neck squamous cell carcinoma.