The results showed that the transcription levels of CXCL1, CXCL2, CXCL3, CXCL5, CXCL6, CXCL8, CXCL9, CXCL10, CXCL11, and CXCL13 in HNSCC samples were significantly higher than those in normal samples. Here, CXCL9 is linked to head and neck squamous cell carcinoma.