SATB1 and malignant colon neoplasm: In mice modeled with colon cancer, deletion of ubiquitin-specific protease 47 (USP47) can impair the transcriptional activity of the target gene special AT-rich sequence binding protein 1 (SATB1), thus inhibiting the proliferative and migratory capacities, as well as tumorigenicity of colon cancer cells (12).