LDLR and familial hyperaldosteronism: A preferred general term is autosomal dominant hypercholesterolemia (ADH), with FH being reserved for the most common form of the disease due to loss-of-function mutations in the low-density lipoprotein receptor (LDLR) gene, which is responsible for hepatic clearance of low-density lipoprotein (LDL) from the blood circulation, and the disease is also known as ADH-1 [3]. ADH can also be caused by loss-of-function mutations in the apolipoprotein B-100 (APOB) gene, which encodes the ligand for LDLR; in this case, the disease should be referred to as familial defective APOB (FDB) or ADH-2 [4].