TNFSF11 and metastasis: Histological analyses of bone lesions in PCa bone metastasis have shown that both osteopenic and osteodense lesions exist in “osteoblastic” lesions (Roudier et al., 2008), and available treatment options for patients diagnosed with PCa bone metastasis mainly include bisphosphonates and anti‐RANKL therapies, both of which are potent and specific bone‐resorption inhibitors.