CASP3 and ovarian neoplasm: To get insight into the effects of different treatments on ovarian tumor morphology and markers of proliferation and apoptosis, we performed H&E and IHC analysis of representative PDX-0113 tumors tissues with the following antibodies: human cytokeratin (CK), PAX8, pS6, Ki67 and cleaved caspase-3 (Figure 5B and Supplementary Figure 6).