Yoon et al. [15] (Yoon, Kwon et al. 2016) discovered a combination of six biomarkers (HE4, CEA, RANTES, ApoA2, TTR, and sVCAM-1) with a sensitivity of 93.33% and specificity of 92.00% in the diagnosis of lung cancer. This evidence concerns the gene CEACAM5 and lung cancer.