Recently, scholars attempted to construct models [24, 25] and scoring systems to predict the resolution of T2D after bariatric surgery, such as the ABCD (age, BMI, C-peptide, and duration of T2D) [26], Integrated Medical Services (duration of T2D, preoperative number of diabetes medications, insulin use, and HbA1c) [27], DiaRem (age, HbA1c, antidiabetic drugs, and insulin treatment) [28], and Diabetes Risk Score (age, duration of T2D, BMI, microvascular and macrovascular complications, insulin use, and stimulated C-peptide level) [29], to predict the resolution of T2D after bariatric surgery. The gene discussed is INS; the disease is diabetes mellitus.