In one of these studies, tumor samples from 222 patients with upper tract urothelial carcinomas who were treated with radical nephroureterectomy were analyzed for the expression of seven basal/luminal immunohistochemical markers (CK5, EGFR, CD44, CK20, p63, GATA3, and FOXA). The gene discussed is KRT5; the disease is renal pelvis/ureter urothelial carcinoma.