CD8A and neoplasm: On the one hand, cDC1 can attract T cells in the tumor, to stimulate and magnified the role of tumor specific CD8+ T cells, meanwhile, which can induce the death of tumor cells and the drainage of tumor antigens to lymph nodes (34, 35), where the formation is responsible for the staggered start anti-tumor key DC subtype of CD8+ T cells, so as to achieve the effect of the removal of the tumor (36).