KCNMB1 and chronic obstructive pulmonary disease: Decreased levels of miR-637 in COPD pulmonary artery smooth muscle cells (PASMCs) are related to pulmonary hypertension (84), while miR-197 is involved in ASMCs proliferation and phenotype (85), and miR-183 expression is augmented in blood from COPD and related to disease severity, targeting KCNMB1 in lungs and smooth muscle cells (99).