IL21 and colorectal carcinoma: In particular, IL-1β, IL-2, IFN-γ, P-selectin, MIP-1α, IL-6, IL-17A, TNF-α, MCP-1, IL-9, IL-1α, IP-10, and IL-8 were increased significantly in CRC compared to CRC-S (Figure 2), whereas IL-27, IL-21, IL-22, IL-18, IL-5, GM-CSF, and sICAM1 showed a similar but not significant trend (p > 0,05).