The relevant higher percentages of chemokines MCP-1, MIP-1α, IL-8, and IP-10 reflect the high colonic inflammation, and many studies demonstrate their role in the development of a tumor-favoring microenvironment due to their abilities to favor angiogenesis and to stimulate macrophages and CD8+ T cell recruitment in situ (63–65). Here, CXCL10 is linked to neoplasm.