MAP2K5 and familial papillary or follicular thyroid carcinoma: In the present study, our large series of Italian unrelated FNMTC kindreds, in which we previously excluded a role for HABP2 and MAP2K5 germline variants (27, 32, 33), has been found not to harbor the DUOX2 p.Y1203H variant, recently described in a non-syndromic FNMTC family (34).