CRP and hypertensive disorder: Prior reviews (Spitznagel et al., 2015; Handley et al., 2016; Nota et al., 2020) have emphasized that the weight loss-related resolution of somatic comorbidities might play a more important role, including Type 2 diabetes (T2D) (Cheke et al., 2017), hypertension (Walker et al., 2017), sleep apnea (Olaithe et al., 2018) and metabolic inflammation (often measured via C-reactive protein (CRP) levels) (Allison and Ditor, 2014).