BRCA2 and pure red-cell aplasia: Recently published guidance from ESMO ‘Clinical Practice Guidelines for diagnosis, treatment and follow-up’ also recommends germline testing for BRCA2 and other DNA repair genes in all men with advanced/metastaticPrCa, regardless of tumour features or FH status, and in all men diagnosed with PrCa with a FH of cancer (at least two close relatives on the same side of the family) linked to hereditary cancer syndromes (ie breast, ovarian, pancreatic, prostate).