It is likely that CCR5 plays a broader role in governing cancer metastasis as maraviroc and vicriviroc reduced prostate cancer cell metastasis to the bones, brain, and viscera in immune-competent mice [22] and reduced metastasis or cellular migration in glioblastoma [54] and a variety of other malignancies [18]. This evidence concerns the gene CCR5 and Familial prostate cancer.