The genes enriched in the apoptotic pathway were intersected with the differentially expressed genes in PCOS, and 9 genes were obtained, namely BID, PIK3CD, TNFRSF10C, TNFRSF1A, MYD88, PIK3R5, PRKACA, MAP 3 K14, PPP3R2 (Fig. 2b). The gene discussed is TNFRSF1A; the disease is polycystic ovary syndrome.