In total AML and cytogenetically normal AML (CN-AML) patients, Kaplan–Meier analysis showed that only LEP expression was positively associated with OS (P = 0.013 and 0.007, Fig. 1a) and LFS (P = 0.025 and 0.062, Additional file 2: Figure S1), suggesting the prognostic effect of LEP expression in AML. Here, LEP is linked to acute myeloid leukemia.