Analysis of CXCL10 and IL6 secretion in a panel of EGFR-dependent human HNSCC cell lines that includes these two cell lines as well as five others (Cal27, HN6, HN12, HN31 and JHU-011) provided further evidence for marked heterogeneity of induction of these two IFN-stimulated genes among the seven cell lines (Fig. 2b). The gene discussed is CXCL10; the disease is head and neck squamous cell carcinoma.