Among Pan-NETs, insulinomas were weaker stained for CgA than the non-β-cell tumors, including gastrinomas, glucagonomas, pancreatic polypeptidomas, and non-functioning Pan-NETs [14,16], and these non-β-cell Pan-NETs are more aggressive than insulinomas [14,16]. This evidence concerns the gene CGA and gastrin-producing neuroendocrine tumor.