In mice, Kcna1 deletion and missense mutations cause increased basket cell excitability leading to excessive inhibition of Purkinje cells, which can lead to stress‐induced motor dysfunction resembling the episodic ataxia in humans due to KCNA1 mutations (Browne et al., 1994; Herson et al., 2003; Zhang et al., 1999). This evidence concerns the gene KCNA1 and Familial paroxysmal ataxia.