SIRPA and atherosclerosis: Dysregulation of the CD47: SIRPα axis could also underlie atherosclerosis progression in humans, as was implied by the observation that the long non-coding RNA (lncRNA) myocardial infarction associated transcript (MIAT) was significantly higher in the circulating sera of atherosclerosis patients and those with symptoms of vulnerable atherosclerotic plaque, compared to controls, indicating that MIAT may also serve as a useful biomarker of plaque stability and atherosclerosis severity.71