ABCA1 and atherosclerosis: miRNA-17-5p—a potentially useful, circulating biomarker for monitoring atherosclerosis severity,62 has also been implicated in the regulation of inflammation and macrophage lipid accumulation during atherosclerosis, through the direct regulation of ATP-binding cassette transporter A1 (ABCA1), a critical component of cellular reverse cholesterol transport/lipid efflux.63