CYBB and atrial fibrillation: As documented in Figure 2 (Supplementary material online, Table S1), atrial burst pacing provoked AF (with episodes of rapid atrial activity lasting >2 s) in a greater proportion of NOX2-Tg than WT (88% vs. 69%, respectively, P = 0.037; Figure 2B), and similar trends were observed when longer bouts of AF (e.g. >5 s and >10) were evaluated (Supplementary material online, Table S1).