Since two independent PCa prognostic factors were delineated using the Sboner data set as our training data set, we sought to predict survival based on YWHAZ and NDRG1 in three other independent non-overlapping validation data sets: TCGA-PRAD (n = 499), Ross-Adams (n = 206)25, and Jenkins (n = 596)26. This evidence concerns the gene NDRG1 and posterior cortical atrophy.