To that end we analyzed RNA-Seq data from normal CD34-positive cells obtained from human bone marrow (GSE102881, GSE111085, GSE63569, and GSE69239), umbilical cord blood (GSE48846, GSE69905, and GSE71689) and peripheral blood (GSE102881, GSE107218, GSE68925, GSE87285, GSE90552 and GSE92274) in addition to AML cells with normal karyotype (GSE49642 and GSE52656), inv(16) (GSE108266, GSE62190, and GSE67039) or a rearranged MLL locus (GSE52656, GSE62190, and GSE67039). This evidence concerns the gene CD34 and acute myeloid leukemia.