SRSF1 and glioblastoma: Importantly, we discovered that the level of MAML2 pre-mRNA was elevated and that of mature MAML2 mRNA was reduced in T98G and U343 cells when SRSF1 or LINC01152 was silenced (Fig. 5I, J), indicating the participation of SRSF1 in the shearing of MAML2 in the nucleus of GBM cells.