Consistent with the result of TWAS, eighteen genes, ANXA5, AP4B1, ATIC, C12orf65, CMAH, PDHB, RUNX3, SBF1, SH2B3, STK38, TMEM43, XPNPEP1, KIAA1530, NUFIP2, PPP2R3C, RAB24, STX6, and TLR5, have been reported differently expressed in peripheral blood mononuclear cells of RA patients. This evidence concerns the gene XPNPEP1 and rheumatoid arthritis.