On the same group of anti-HCV positive HD patients, we were able to show that major homozygosity in rs368234815 (TT/TT) similarly predicts spontaneous HCV clearance in the dominant model of inheritance as other tested IFNL3/IFNL4 polymorphisms already associated with HCV clearance in HD subjects. The gene discussed is IFNL3; the disease is Huntington disease.