TNF and COVID-19: COVID-19 is also characterized by a “cytokine storm” with increased levels of pro-inflammatory cytokines in the blood, such as IL-1β, TNF-α, IL-6, IL-12 [4,67,68,80], and we detected increased IL-1β, IL-6, IL-12, IL-23, and IL-27 in the serum following ORN06 aspiration.