The immunostaining analysis reveals high levels of the αVβ3 integrin (Figs 1 and 2, top panels) which correlate with SYP expression (Figs 1 and 2, bottom panels) in the prostate tumors (Fig 1) and lung metastatic lesions (Fig 2) of DKO and TKO mice (n = 5 for each group). This evidence concerns the gene SYP and prostate neoplasm.