ABCG2 and early-onset autosomal dominant Alzheimer disease: Not surprisingly, the most notable pathways dominating in TB patients (e.g., environmental information processing, membrane transport, ABC transporters, transcription, signal transduction, etc.)have been reported to be upregulated in other diseases e.g., auto inflammatory and autoimmune disorders, chronic periodontitis, cystic fibrosis, Alzheimer’s disease, etc. [70–73].