Not surprisingly, the most notable pathways dominating in TB patients (e.g., environmental information processing, membrane transport, ABC transporters, transcription, signal transduction, etc.)have been reported to be upregulated in other diseases e.g., auto inflammatory and autoimmune disorders, chronic periodontitis, cystic fibrosis, Alzheimer’s disease, etc. [70–73]. This evidence concerns the gene ABCG2 and chronic periodontitis.