LRRK2 and Parkinson disease: Lysosomal dysregulation and associated α‐synuclein aggregation appear to be a central event in the pathogenesis of PD (Alessi & Sammler, 2018) and LRRK2, through its regulation of the endolysosomal pathways, is a key player in this mechanism (Henry et al, 2015; Roosen & Cookson, 2016; Vidyadhara et al, 2019; Kuwahara & Iwatsubo, 2020).