Both astroblastoma-like tumors displayed novel gene fusions with case 16 harboring a unique PATZ1 (exon1)-MN1 (exon1) gene fusion and case 17 carrying MYH9 (exon 3)-SEC14L2 (exon 2) and MTMR3 (exon 2)-NCOA3 (exon 10) fusion transcripts. The gene discussed is MYH9; the disease is astroblastoma.