To determine whether sequential DNMTi and HDACi cooperate with the absence of myeloid NF‐κB p50 to slow Nb tumor growth, p50(f/f);Lys‐Cre mice were inoculated with 9464D cells and then on day 33 began to receive azacytidine for 5 days followed by ITF‐2357 (Givinostat) for 5 days, on alternating weeks until the end of the study. This evidence concerns the gene NFKB1 and neoplasm.