Notably, depletion of CD4+ T cells alone also increased the rate of tumor growth, but to a lesser extent (Fig. S4B), depletion of CD8+ T cells alone did not accelerate tumor growth (Fig. S4C), indicating that both CD4+ and CD8+ T cells make important contributions to slowed Nb tumor growth in p50(f/f);Lys‐Cre mice. This evidence concerns the gene CD8A and neoplasm.