Melanoma, fibrosarcoma, colon cancer, glioblastoma, prostate cancer, and pancreatic ductal carcinoma each grow slower in syngeneic B6 p50−/− than in wild‐type (WT) mice, with M2‐to‐M1 TAM reprogramming and increased tumor T‐cell activation evident in p50−/− tumor hosts [14, 15, 16, 17]. The gene discussed is NFKB1; the disease is malignant colon neoplasm.