CLOCK and viral infectious disease: In numerous models of viral infection as well as asepticinflammation, the disruption of the clock incurred by the loss ofBmal1 in key cell types results in increased diseaseseverity (Scheiermann etal., 2012; Gibbs et al., 2014; Sutton et al., 2017; Early et al.,2018; Ehlers et al., 2018; Pariollaud et al., 2018; Sengupta et al.,2019; Z.Zhang et al., 2019).