Also, in the GSE81861 dataset, among 103 non-epithelial cells from human colorectal cancer tissues, ACE2 was expressed by 33% of endothelial cells; TMPRSS2 was expressed by 7.6% of B cells, 5.9% of fibroblasts, 11% of macrophages, and 3% of T cells (Fig. 4B). This evidence concerns the gene TMPRSS2 and colorectal cancer.