As shown in Fig. 1G and Table 2, the expression of Rab10 was higher in osteosarcoma tissues (21/29) compared with that in non-neoplastic bone tissues (5/27), and the expression of Rab10 was found to be associated with pulmonary metastasis (P < 0.001) and TNM stage (AJCC) (P < 0.001). The gene discussed is RAB10; the disease is osteosarcoma.