There were no significant differences in age, patients with hypertension at diagnosis, patients with diabetes mellitus at diagnosis, patients with diabetes mellitus at diagnosis, patients with cardiovascular diseases at diagnosis, ESR, hemoglobin, serum albumin, 24 h-proteinuria, urine RBC counts, complement C3, complement C4, HDL-C, LDL-C, anti-MPO, anti-PR3 and BVAS between the patients in two groups (Table 1). The gene discussed is PRTN3; the disease is diabetes mellitus.