AKT1 and cancer: We could also found some dominant pathways both Low and High group expressed in common, including “Steroid biosynthesis, Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, TNF signaling pathway, PI3K-Akt signaling pathway, MAPK signaling pathway, Transcriptional misregulation in cancer and ECM-receptor interaction”, so some critical pathways and related DEGs were listed in Table 3.